MAGI3 enhances sensitivity to sunitinib in renal cell carcinoma by suppressing the MAS/ERK axis and serves as a prognostic marker

MAGI3 enhances sensitivity to sunitinib in renal cell carcinoma by suppressing the MAS/ERK axis and serves as a prognostic marker

Abstract Clear cell renal cell carcinoma (ccRCC) exhibits considerable heterogeneity, with approximately 25% of localized cases susceptible to relapse, highlighting the challenge of the absence of reliable predictive biomarkers for personalized treatment. Meanwhile, metastatic renal cell carcinoma i...

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Bibliographic Details
Main Authors: Haibo Wang, Yibin Chen, Ying Yang, Ran Song, Siyu Gu, Xuedi Cao, Lijie Zhang, Yang Yang, Tianzhong Hou, Xuan Qi, Yumeng Yang, Yue Wang, Tao Bai, Duiping Feng, Xiaomei Yang, Junqi He
Format: Article
Language:English
Published: Nature Publishing Group 2025-02-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-025-07427-0

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https://doi.org/10.1038/s41419-025-07427-0

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