Suppressive effects of vitamin C-treated induced-regulatory T cells on heart allograft rejection under vitamin C-deficient or -sufficient conditions.

Suppressive effects of vitamin C-treated induced-regulatory T cells on heart allograft rejection under vitamin C-deficient or -sufficient conditions.

Foxp3 stability of vitamin C-treated induced-regulatory T cells (V-iTregs) is superior to that of conventional iTregs (C-iTregs). However, the role of V-iTregs in allograft rejection under vitamin C-deficient conditions, such as those seen in humans, remains unclear. We aimed to elucidate the role o...

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Bibliographic Details
Main Authors: Ju Hee Hwang, Honglin Piao, Joon Young Jang, Sun-Kyung Lee, Dongkyu Han, Gwang-Min Lee, Cheolhyeon Go, Yejin Kim, Kwon Ik Oh, Jae Seung Kang, Ji-Jing Yan, Jaeseok Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0246967

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https://doi.org/10.1371/journal.pone.0246967

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