Staged use of ordinal and linear disability scales: a practical approach to granular assessment of acute stroke outcome

Staged use of ordinal and linear disability scales: a practical approach to granular assessment of acute stroke outcome

BackgroundThe modified Rankin Scale (mRS) assessment of global disability is the most common primary endpoint in acute stroke trials but lacks granularity (7 broad levels) and is ordinal (scale levels unknown distances apart), which constrains study power. Disability scales that are linear and conti...

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Bibliographic Details
Main Authors: Napasri Chaisinanunkul, Sidney Starkman, Jeffrey Gornbein, Scott Hamilton, Fiona Chatfield, Robin Conwit, Jeffrey L. Saver
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Neurology
Subjects:
cerebrovascular disease/stroke
acute cerebral hemorrhage
acute cerebral infarction
acute stroke syndromes
emergency treatment of stroke
outcome assessment
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2023.1174686/full

Internet

https://www.frontiersin.org/articles/10.3389/fneur.2023.1174686/full

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