Ligament injury in adult zebrafish triggers ECM remodeling and cell dedifferentiation for scar-free regeneration

Abstract After traumatic injury, healing of mammalian ligaments is typically associated with fibrotic scarring as opposed to scar-free regeneration. In contrast, here we show that the ligament supporting the jaw joint of adult zebrafish is capable of rapid and complete scar-free healing. Following s...

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Bibliographic Details
Main Authors: Troy Anderson, Julia Mo, Ernesto Gagarin, Desmarie Sherwood, Maria Blumenkrantz, Eric Mao, Gianna Leon, Hailey Levitz, Hung-Jhen Chen, Kuo-Chang Tseng, Peter Fabian, J. Gage Crump, Joanna Smeeton
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:npj Regenerative Medicine
Online Access:https://doi.org/10.1038/s41536-023-00329-9