Ventricular stabilization with a customized decellularized cardiac ECM-based scaffold after myocardial infarction alters gene expression in a rodent LAD-ligation model

Ventricular stabilization with a customized decellularized cardiac ECM-based scaffold after myocardial infarction alters gene expression in a rodent LAD-ligation model

Objectives: Decellularized extracellular matrix (dECM) is increasingly used in a wide range of regenerative medicine applications and may also offer the potential to support injured myocardium. Here, we evaluated the myocardial gene expression pattern after myocardial infarction (MI) in a standardiz...

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Bibliographic Details
Main Authors: Hug Aubin, Lenard Rath, Alexandra Vey, Vera Schmidt, Mareike Barth, Elvira Weber, Artur Lichtenberg, Payam Akhyari
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
myocardial infarction
decellularized extracellular matrix
gene expression
tissue engineering
cardiac regeneration
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.896269/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2022.896269/full

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