Microglia P2X4 receptors as pharmacological targets for demyelinating diseases

Pharmacological activation of the P2X4 receptor expressed by brain microglia may provide a novel avenue to promote remyelination and improve clinical symptoms in experimental autoimmune encephalomyelitis and potentially in multiple sclerosis.

Bibliographic Details
Main Authors: Francesco Di Virgilio, Alba Clara Sarti
Format: Article
Language:English
Published: Springer Nature 2018-08-01
Series:EMBO Molecular Medicine
Online Access:https://doi.org/10.15252/emmm.201809369