HNF4α Acts as Upstream Functional Regulator of Intestinal Wnt3 and Paneth Cell FateSummary
Background & Aims: The intestinal epithelium intrinsically renews itself ex vivo via the proliferation of Lgr5+ intestinal stem cells, which is sustained by the establishment of an epithelial stem cell niche. Differentiated Paneth cells are the main source of epithelial-derived niche factor...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-01-01
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Series: | Cellular and Molecular Gastroenterology and Hepatology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2352345X22002466 |