Pupillary reflex and behavioral masking responses to light as functional measures of retinal degeneration in mice.

<h4>Background</h4>Pre-clinical testing of retinal pathology and treatment efficacy depends on reliable and valid measures of retinal function. The electroretinogram (ERG) and tests of visual acuity are the ideal standard, but can be unmeasurable while useful vision remains. Non-image-fo...

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Bibliographic Details
Main Authors: Ethan O Contreras, Carley G Dearing, Crystal A Ashinhurst, Betty A Fish, Sajila N Hossain, Ariana M Rey, Primal D Silva, Stewart Thompson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0244702