Cx43 can form functional channels at the nuclear envelope and modulate gene expression in cardiac cells

Cx43 can form functional channels at the nuclear envelope and modulate gene expression in cardiac cells

Classically associated with gap junction-mediated intercellular communication, connexin43 (Cx43) is increasingly recognized to possess non-canonical biological functions, including gene expression regulation. However, the mechanisms governing the localization and role played by Cx43 in the nucleus,...

Full description

Bibliographic Details
Main Authors: Tania Martins-Marques, Katja Witschas, Ilda Ribeiro, Mónica Zuzarte, Steve Catarino, Teresa Ribeiro-Rodrigues, Francisco Caramelo, Trond Aasen, Isabel Marques Carreira, Lino Goncalves, Luc Leybaert, Henrique Girao
Format: Article
Language:English
Published: The Royal Society 2023-11-01
Series:Open Biology
Subjects:
connexin43
nuclear translocation
subcellular trafficking
gene expression
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsob.230258

Internet

https://royalsocietypublishing.org/doi/10.1098/rsob.230258

Similar Items