Genetic characterization of outbred Sprague Dawley rats and utility for genome-wide association studies.

Sprague Dawley (SD) rats are among the most widely used outbred laboratory rat populations. Despite this, the genetic characteristics of SD rats have not been clearly described, and SD rats are rarely used for experiments aimed at exploring genotype-phenotype relationships. In order to use SD rats t...

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Bibliographic Details
Main Authors: Alexander F Gileta, Christopher J Fitzpatrick, Apurva S Chitre, Celine L St Pierre, Elizabeth V Joyce, Rachael J Maguire, Africa M McLeod, Natalia M Gonzales, April E Williams, Jonathan D Morrow, Terry E Robinson, Shelly B Flagel, Abraham A Palmer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-05-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1010234