Metabolomic differentiation of benign vs malignant pulmonary nodules with high specificity via high-resolution mass spectrometry analysis of patient sera

Metabolomic differentiation of benign vs malignant pulmonary nodules with high specificity via high-resolution mass spectrometry analysis of patient sera

Abstract Differential diagnosis of pulmonary nodules detected by computed tomography (CT) remains a challenge in clinical practice. Here, we characterize the global metabolomes of 480 serum samples including healthy controls, benign pulmonary nodules, and stage I lung adenocarcinoma. The adenocarcin...

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Bibliographic Details
Main Authors: Yao Yao, Xueping Wang, Jian Guan, Chuanbo Xie, Hui Zhang, Jing Yang, Yao Luo, Lili Chen, Mingyue Zhao, Bitao Huo, Tiantian Yu, Wenhua Lu, Qiao Liu, Hongli Du, Yuying Liu, Peng Huang, Tiangang Luan, Wanli Liu, Yumin Hu
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-37875-1

Internet

https://doi.org/10.1038/s41467-023-37875-1

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