A biophysical approach of cytarabine anticancer drug insights into human serum albumin and checkpoint kinase 1

A biophysical approach of cytarabine anticancer drug insights into human serum albumin and checkpoint kinase 1

The present studies used biophysical techniques to examine the binding interaction mechanism of cytarabine anticancer drugs with human serum albumin (HSA) and checkpoint kinase 1. The UV–vis absorption spectrum of the cytarabine-HSA complex reveals a blue shift due to the presence of the cytarabine...

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Bibliographic Details
Main Authors: Manoharan Rupavarshini, Subramani Karthikeyan, Sundaramoorthy Anandh, Anitha Ramamoorthi, Suganya Ramakrishnamurthy, Ganesan Bharanidharan, Prakasarao Aruna, Rajendiran Mangaiyarkarasi, Shanmugavel Chinnathambi, Ganesh N. Pandian, Singaravelu Ganesan
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Results in Chemistry
Subjects:
Cytarabine – anticancer drug
Drug binding pocket
FRET
Molecular docking
Molecular dynamics
Density Functional Theory
Online Access:http://www.sciencedirect.com/science/article/pii/S221171562200474X

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http://www.sciencedirect.com/science/article/pii/S221171562200474X

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