Characterisation of the blood RNA host response underpinning severity in COVID-19 patients

Abstract Infection with SARS-CoV-2 has highly variable clinical manifestations, ranging from asymptomatic infection through to life-threatening disease. Host whole blood transcriptomics can offer unique insights into the biological processes underpinning infection and disease, as well as severity. W...

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Bibliographic Details
Main Authors: Heather Jackson, Irene Rivero Calle, Claire Broderick, Dominic Habgood-Coote, Giselle D’Souza, Samuel Nichols, Ortensia Vito, Jose Gómez-Rial, Carmen Rivero-Velasco, Nuria Rodríguez-Núñez, Gema Barbeito-Castiñeiras, Hugo Pérez-Freixo, Manuel Barreiro-de Acosta, Aubrey J. Cunnington, Jethro A. Herberg, Victoria J. Wright, Alberto Gómez-Carballa, Antonio Salas, Michael Levin, Federico Martinon-Torres, Myrsini Kaforou, PERFORM consortium, GEN-COVID (www.gencovid.eu) study group
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-15547-2