Greater white matter degeneration and lower structural connectivity in non-amnestic vs. amnestic Alzheimer’s disease

Greater white matter degeneration and lower structural connectivity in non-amnestic vs. amnestic Alzheimer’s disease

IntroductionMultimodal evidence indicates Alzheimer’s disease (AD) is characterized by early white matter (WM) changes that precede overt cognitive impairment. WM changes have overwhelmingly been investigated in typical, amnestic mild cognitive impairment and AD; fewer studies have addressed WM chan...

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Bibliographic Details
Main Authors: Jeffrey S. Phillips, Nagesh Adluru, Moo K. Chung, Hamsanandini Radhakrishnan, Christopher A. Olm, Philip A. Cook, James C. Gee, Katheryn A. Q. Cousins, Sanaz Arezoumandan, David A. Wolk, Corey T. McMillan, Murray Grossman, David J. Irwin
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Neuroscience
Subjects:
diffusion MRI (dMRI)
non-amnestic Alzheimer’s disease
logopenic variant of primary progressive aphasia (lvPPA)
posterior cortical atrophy (PCA)
corticobasal syndrome (CBS)
behavioral variant Alzheimer’s disease
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2024.1353306/full

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https://www.frontiersin.org/articles/10.3389/fnins.2024.1353306/full

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