The GM2 glycan serves as a functional coreceptor for serotype 1 reovirus.
Viral attachment to target cells is the first step in infection and also serves as a determinant of tropism. Like many viruses, mammalian reoviruses bind with low affinity to cell-surface carbohydrate receptors to initiate the infectious process. Reoviruses disseminate with serotype-specific tropism...
| Glavni autori: | , , , , , , , |
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| Format: | Članak |
| Jezik: | English |
| Izdano: |
Public Library of Science (PLoS)
2012-01-01
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| Serija: | PLoS Pathogens |
| Online pristup: | https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1003078&type=printable |