Folic acid ameliorates celecoxib cardiotoxicity in a doxorubicin heart failure rat model

Context: The cardiotoxic effect of selective cyclo-oxygenase-2 inhibitors is well known. While rofecoxib and valdecoxib have been withdrawn, celecoxib remains on the market. Folic acid, a naturally occurring vitamin, has been shown to reduce myocardial ischemia and post-reperfusion injury in rats. O...

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Bibliographic Details
Main Authors: Shafique Ahmad, Bibhu Prasad Panda, Kanchan Kohli, Mohammad Fahim, Kiran Dubey
Format: Article
Language:English
Published: Taylor & Francis Group 2017-01-01
Series:Pharmaceutical Biology
Subjects:
Online Access:http://dx.doi.org/10.1080/13880209.2017.1299768