Immunogenicity and protective efficacy of human metapneumovirus virus-like particles produced by a recombinant baculovirus in mice

Immunogenicity and protective efficacy of human metapneumovirus virus-like particles produced by a recombinant baculovirus in mice

Background: Human metapneumovirus (HMPV) causes respiratory tract infections among infant, elderly, and immunocompromised patients, with significant mortality. Currently no licensed vaccines or therapeutic agents of HMPV exist. Methods: HMPV virus-like particle (VLP) was constructed by co-expressing...

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Bibliographic Details
Main Authors: Fenlian Ma, Aijun Chen, Lihong Yao, Hanchun Gao, Qian Zhang, Wenzhe Hou, Lishu Zheng
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Virus Research
Subjects:
Human metapneumovirus
Virus-like particle
Immunogenicity
Protective efficacy
Online Access:http://www.sciencedirect.com/science/article/pii/S0168170223001776

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http://www.sciencedirect.com/science/article/pii/S0168170223001776

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