ProHSO4: An efficient catalyst for solvent-free synthesis of bis(indolyl)methanes and their in silico screening for potential biological activity

ProHSO4: An efficient catalyst for solvent-free synthesis of bis(indolyl)methanes and their in silico screening for potential biological activity

A simple, mild, and efficient protocol has been developed for the synthesis of 3,3′-bis(indolyl)methanes (BIMs) using prolinium hydrogen sulfate (ProHSO4) as a catalyst under solvent-free and support-free conditions. This mechanochemical method undergoes electrophilic substitution reaction of indole...

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Bibliographic Details
Main Authors: Vikrant Kumbhar, Rutik Raskar, Radha Chafle, Vandana Nikam, Avinash Kumbhar, Ramdas Pawar, Manohar Chaskar, Gulab Gugale, Bhushan Khairnar
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Results in Chemistry
Subjects:
Bis(indolyl)methanes
ProHSO4
Eg5 kinesin
Human p38 α MAP Kinase
Human 3 alpha HSD type 3
Online Access:http://www.sciencedirect.com/science/article/pii/S221171562300262X

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http://www.sciencedirect.com/science/article/pii/S221171562300262X

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