Selection, characterization and in vivo evaluation of novel CD44v6-targeting antibodies for targeted molecular radiotherapy

Abstract Molecular radiotherapy combines the advantages of systemic administration of highly specific antibodies or peptides and the localized potency of ionizing radiation. A potential target for molecular radiotherapy is the cell surface antigen CD44v6, which is overexpressed in numerous cancers,...

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Bibliographic Details
Main Authors: A. C. L. Mortensen, H. Berglund, L. Segerström, M. Walle, C. Hofström, H. Persson, P.-Å. Nygren, J. Nilvebrant, F. Y. Frejd, M. Nestor
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-47891-2