Generation of hiPSCs with ABO c.767T>C substitution: resulting in splicing variants

Generation of hiPSCs with ABO c.767T>C substitution: resulting in splicing variants

Introduction: The ABO blood group system has important clinical significance in the safety of blood transfusion and organ transplantation. Numerous ABO variations, especially variations in the splice sites, have been identified to be associated with some ABO subtypes.Methods: Here, we performed the...

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Bibliographic Details
Main Authors: Yinge Jin, Tao Chen, Wei Zheng, Jiahui Xi, Yin Zi, Jinling Wang, Yue Chi, Min Chen, Qingjian Zou, Chengcheng Tang, Liangxue Lai, Xiaoqing Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Genetics
Subjects:
base substitution
ABO gene
hiPSC
splicing variants
rare subtype
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1141756/full

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https://www.frontiersin.org/articles/10.3389/fgene.2023.1141756/full

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