The Leydig cell biomarker INSL3 as a predictor of age-related morbidity: Findings from the EMAS cohort

The Leydig cell biomarker INSL3 as a predictor of age-related morbidity: Findings from the EMAS cohort

BackgroundInsulin-like peptide 3 (INSL3) is a constitutive hormone secreted in men by the mature Leydig cells of the testes. It is an accurate biomarker for Leydig cell functional capacity, reflecting their total cell number and differentiation status.ObjectivesTo determine the ability of INSL3 to p...

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Bibliographic Details
Main Authors: Richard Ivell, Kee Heng, Katie Severn, Leen Antonio, Gyorgy Bartfai, Felipe F. Casanueva, Ilpo T. Huhtaniemi, Aleksander Giwercman, Mario Maggi, Daryl B. O’Connor, Terence W. O’Neill, Margus Punab, Giulia Rastrelli, Jolanta Slowikowska-Hilczer, Jos Tournoy, Dirk Vanderschueren, Frederick C. W. Wu, Ravinder Anand-Ivell
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Endocrinology
Subjects:
sexual function
hypertension
hypogonadism
cardiovascular disease
frailty
bone mineral density
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.1016107/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2022.1016107/full

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