Tobacco exposure primes the secretion of CCL21 positively associated with tertiary lymphoid structure and response to immunotherapy

Background It has been reported that smoking history as a predictor of immunotherapy efficacy in patients with advanced lung cancer, however, the underlying mechanisms of this phenomenon remain largely unknown.Methods The patients with lung adenocarcinoma’s (LUAD) cohort and the orthotopical transpl...

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Bibliographic Details
Main Authors: Feng Jiang, Qixing Mao, Lin Xu, Bing Chen, Xuewen Yin, Rutao Li, Xuming Song, Te Zhang, Yingkuan Liang, Yu-Zhong Chen, Xinnian Yu, Wenjie Xia, Gaochao Dong
Format: Article
Language:English
Published: BMJ Publishing Group 2023-06-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/11/6/e006939.full