Captopril, a Renin-Angiotensin System Inhibitor, Attenuates Features of Tumor Invasion and Down-Regulates C-Myc Expression in a Mouse Model of Colorectal Cancer Liver Metastasis

Captopril, a Renin-Angiotensin System Inhibitor, Attenuates Features of Tumor Invasion and Down-Regulates C-Myc Expression in a Mouse Model of Colorectal Cancer Liver Metastasis

(1) Background: Recent clinical and experimental data suggests that the liver’s regenerative response following partial hepatectomy can stimulate tumor recurrence in the liver remnant. The Wnt/β-catenin pathway plays important roles in both colorectal cancer carcinogenesis and liver regeneration. St...

Full description

Bibliographic Details
Main Authors: Georgina E. Riddiough, Theodora Fifis, Katrina A. Walsh, Vijayaragavan Muralidharan, Christopher Christophi, Bang M. Tran, Elizabeth Vincan, Marcos V. Perini
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Cancers
Subjects:
renin-angiotensin system
liver regeneration
Wnt pathway
c-myc
colorectal liver metastasis
Online Access:https://www.mdpi.com/2072-6694/13/11/2734

Internet

https://www.mdpi.com/2072-6694/13/11/2734

Similar Items