NANOG reporter cell lines generated by gene targeting in human embryonic stem cells.

Pluripotency and self-renewal of human embryonic stem cells (hESCs) is mediated by a complex interplay between extra- and intracellular signaling pathways, which regulate the expression of pluripotency-specific transcription factors. The homeodomain transcription factor NANOG plays a central role in...

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Bibliographic Details
Main Authors: Yvonne Fischer, Elvira Ganic, Jacqueline Ameri, Xiaojie Xian, Martina Johannesson, Henrik Semb
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2932718?pdf=render