Quantification of PD-1/PD-L1 Interaction between Membranes from PBMCs and Melanoma Samples Using Cell Membrane Microarray and Time-Resolved Förster Resonance Energy Transfer

Quantification of PD-1/PD-L1 Interaction between Membranes from PBMCs and Melanoma Samples Using Cell Membrane Microarray and Time-Resolved Förster Resonance Energy Transfer

Melanoma is a carcinoma known to evade the host immune defenses via the downregulation of the immune response. One of the molecules involved in this mechanism is programmed cell death ligand 1 (PD-L1), which interacts with its receptor, programmed cell death protein 1 (PD-1), expressed on T cells, l...

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Bibliographic Details
Main Authors: Lissete Sánchez-Magraner, Miguel de la Fuente, Charles Evans, James Miles, Ane Elexpe, Maddalen Rodriguez-Astigarraga, Egoitz Astigarraga, Gabriel Barreda-Gómez
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Analytica
Subjects:
immunotherapy
protein–protein interaction
melanoma
microarray
amplified FRET
PD-L1/PD-1
Online Access:https://www.mdpi.com/2673-4532/2/4/15

Internet

https://www.mdpi.com/2673-4532/2/4/15

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