Nigral volumetric and microstructural measures in individuals with scans without evidence of dopaminergic deficit

Nigral volumetric and microstructural measures in individuals with scans without evidence of dopaminergic deficit

IntroductionStriatal dopamine transporter (DAT) imaging using 123I-ioflupane single photon positron emitted computed tomography (SPECT) (DaTScan, GE) identifies 5−20% of newly diagnosed Parkinson’s disease (PD) subjects enrolling in clinical studies to have scans without evidence of dopaminergic def...

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Bibliographic Details
Main Authors: Jason Langley, Kristy S. Hwang, Xiaoping P. Hu, Daniel E. Huddleston
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Neuroscience
Subjects:
scans without evidence of dopaminergic deficit
Parkinson’s disease
neuromelanin
substantia nigra pars compacta
free water
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2022.1048945/full

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https://www.frontiersin.org/articles/10.3389/fnins.2022.1048945/full

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