Genetic similarity of chromosome 6 between patients receiving hematopoietic stem cell transplantation and HLA matched sibling donors

Background Matching for HLA genes located on chromosome 6 is required in hematopoietic stem cell transplantation to reduce the incidence of graft-versus-host disease. However, a considerable proportion of patients still suffer from it, obviously due to genetic differences outside the HLA gene region...

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Bibliographic Details
Main Authors: Hannu Turpeinen, Liisa Volin, Lauri Nikkinen, Pauli Ojala, Aarno Palotie, Janna Saarela, Jukka Partanen
Format: Article
Language:English
Published: Ferrata Storti Foundation 2009-04-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/5221