Expression of DNMT1 and DNMT3a are regulated by GLI1 in human pancreatic cancer.

Expression of DNMT1 and DNMT3a are regulated by GLI1 in human pancreatic cancer.

GLI1, as an indispensable transcriptional factor of Hedgehog signaling pathway, plays an important role in the development of pancreatic cancer (PC). DNA methyltransferases (DNMTs) mediate the methylation of quantity of tumor-related genes. Our study aimed to explore the relationship between GLI1 an...

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Bibliographic Details
Main Authors: ShanShan He, Feng Wang, LiJuan Yang, ChuanYong Guo, Rong Wan, AiWu Ke, Ling Xu, GuoYong Hu, XuanFu Xu, Jie Shen, XingPeng Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3215738?pdf=render

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http://europepmc.org/articles/PMC3215738?pdf=render

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