Rab11 activation by Ik2 kinase is required for dendrite pruning in Drosophila sensory neurons.

Neuronal pruning is a commonly observed phenomenon for the developing nervous systems to ensure precise wiring of neural circuits. The function of Ik2 kinase and its downstream mediator, Spindle-F (Spn-F), are essential for dendrite pruning of Drosophila sensory neurons during development. However,...

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Bibliographic Details
Main Authors: Tzu Lin, Hao-Hsiang Kao, Che-Hsuan Chou, Chih-Yu Chou, Yu-Ching Liao, Hsiu-Hsiang Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-02-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1008626