Cytokine release syndrome: grading, modeling, and new therapy

Abstract Genetically modified T cells that express a chimeric antigen receptor (CAR) are opening a new frontier in cancer immunotherapy. CAR T cells currently are in clinical trials for many cancer types. Cytokine release syndrome (CRS) and neurotoxicities (CAR-related encephalopathy syndrome, CRES)...

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Bibliographic Details
Main Authors: Delong Liu, Juanjuan Zhao
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Journal of Hematology & Oncology
Online Access:http://link.springer.com/article/10.1186/s13045-018-0653-x