Epigenetic regulation of GABA catabolism in iPSC-derived neurons: The molecular links between FGF21 and histone methylation

Epigenetic regulation of GABA catabolism in iPSC-derived neurons: The molecular links between FGF21 and histone methylation

Objective: Fibroblast growth factor 21 (FGF21) analogs have been tested as potential therapeutics for substance use disorders. Prior research suggests that FGF21 administration might affect alcohol consumption and reward behaviors. Our recent report showed that plasma FGF21 levels were positively co...

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Bibliographic Details
Main Authors: Ming-Fen Ho, Cheng Zhang, Irene Moon, Joanna Biernacka, Brandon Coombes, Quyen Ngo, Cedric Skillon, Michelle Skime, Tyler Oesterle, Paul E. Croarkin, Victor M. Karpyak, Hu Li, Richard M. Weinshilboum
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Molecular Metabolism
Subjects:
FGF21
GABA catabolism
Alcohol use disorder
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877823001321

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http://www.sciencedirect.com/science/article/pii/S2212877823001321

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