Fragile X related protein 1 clusters with ribosomes and messenger RNAs at a subset of dendritic spines in the mouse hippocampus.

The formation and storage of memories in neuronal networks relies on new protein synthesis, which can occur locally at synapses using translational machinery present in dendrites and at spines. These new proteins support long-lasting changes in synapse strength and size in response to high levels of...

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Bibliographic Details
Main Authors: Denise Cook, Maria del Rayo Sanchez-Carbente, Claude Lachance, Danuta Radzioch, Sandra Tremblay, Edouard W Khandjian, Luc DesGroseillers, Keith K Murai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3191184?pdf=render