Loss of STAT5A promotes glucose metabolism and tumor growth through miRNA‐23a‐AKT signaling in hepatocellular carcinoma

Loss of STAT5A promotes glucose metabolism and tumor growth through miRNA‐23a‐AKT signaling in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide. Here, we identified that increased miR‐23a expression in HCC tissues was associated with worse survival. More importantly, we found that STAT5A was a target of miR‐23a, whose levels significantly decreased in tumor tiss...

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Bibliographic Details
Main Authors: Yabo Jiang, Yongzhen Tao, Xiuping Zhang, Xubiao Wei, Min Li, Xuxiao He, Bin Zhou, Weixing Guo, Huiyong Yin, Shuqun Cheng
Format: Article
Language:English
Published: Wiley 2021-02-01
Series:Molecular Oncology
Subjects:
AKT
glucose metabolism
hepatocellular carcinoma
miR‐23a
STAT5A
tumor growth
Online Access:https://doi.org/10.1002/1878-0261.12846

Internet

https://doi.org/10.1002/1878-0261.12846

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