Tel2 regulates redifferentiation of bipotential progenitor cells via Hhex during zebrafish liver regeneration

Summary: Upon extensive hepatocyte loss or impaired hepatocyte proliferation, liver regeneration occurs via biliary epithelial cell (BEC) transdifferentiation, which includes dedifferentiation of BECs into bipotential progenitor cells (BP-PCs) and then redifferentiation of BP-PCs to nascent hepatocy...

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Bibliographic Details
Main Authors: Junren Zhang, Yang Zhou, Shuang Li, Dashuang Mo, Jianlong Ma, Rui Ni, Qifen Yang, Jianbo He, Lingfei Luo
Format: Article
Language:English
Published: Elsevier 2022-04-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124722003448