Estradiol ameliorates antioxidant axis SIRT1-FoxO3a-MnSOD/catalase in the heart of fructose-fed ovariectomized rats

Estradiol ameliorates antioxidant axis SIRT1-FoxO3a-MnSOD/catalase in the heart of fructose-fed ovariectomized rats

Harmful effects of fructose-rich diet (FRD) were predominantly observed in males, suggesting protective effects of estrogens. Little is known about AMPK/sirtuin-1 (SIRT1)/forkhead box O3 (FoxO3a)/manganese superoxide dismutase (MnSOD)/catalase signaling in the heart in state of metabolic syndrome an...

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Bibliographic Details
Main Authors: Maja Boskovic, Maja Bundalo, Maja Zivkovic, Jelena Stanisic, Milan Kostic, Goran Koricanac, Aleksandra Stankovic
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Journal of Functional Foods
Subjects:
Metabolic syndrome
Fructose
Estradiol
Heart
miRNA
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464618306297

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http://www.sciencedirect.com/science/article/pii/S1756464618306297

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