Crosstalk between microRNA and DNA Methylation Offers Potential Biomarkers and Targeted Therapies in ALK-Positive Lymphomas

The discovery of microRNA (miRNA) has provided new and powerful tools for studying the mechanism, diagnosis and treatment of human cancers. The down-regulation of tumor suppressive miRNA by hypermethylation of CpG island (CpG is shorthand for 5′-C-phosphate-G-3′, that is, cytosine and guanine separa...

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Bibliographic Details
Main Authors: Coralie Hoareau-Aveilla, Fabienne Meggetto
Format: Article
Language:English
Published: MDPI AG 2017-08-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/9/8/100