Proteins from Avastin® (bevacizumab) show tyrosine nitrations for which the consequences are completely unclear.

Avastin® (bevacizumab) is a protein drug widely used for cancer treatment although its further use is questionable due to serious side effects reported. As no systematic proteomic study on posttranslational modifications (PTMs) was reported so far, it was the aim of the current study to use a gel-ba...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Jia Wan, Edina Csaszar, Wei-Qiang Chen, Kongzhao Li, Gert Lubec
Format: Artikel
Sprache:English
Veröffentlicht: Public Library of Science (PLoS) 2012-01-01
Schriftenreihe:PLoS ONE
Online Zugang:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22523550/?tool=EBI