Naive T cells inhibit the outgrowth of intractable antigen-activated memory T cells: implications for T-cell immunotherapy

Naive T cells inhibit the outgrowth of intractable antigen-activated memory T cells: implications for T-cell immunotherapy

Background The wider application of T cells targeting viral tumor-antigens via their native receptors is hampered by the failure to expand potent tumor-specific T cells from patients. Here, we examine reasons for and solutions to this failure, taking as our model the preparation of Epstein-Barr viru...

Full description

Bibliographic Details
Main Authors: Malcolm K Brenner, Cliona M Rooney, Sandhya Sharma, Birju Mehta, Helen E Heslop, Michael Schmueck-Henneresse, Huimin Zhang, Mae Woods, Naren U Mehta, Tim Sauer, Kathan S Parikh
Format: Article
Language:English
Published: BMJ Publishing Group 2023-04-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/11/4/e006267.full

Internet

https://jitc.bmj.com/content/11/4/e006267.full

Similar Items