Lower myostatin and higher MUC1 levels are associated with better response to mepolizumab and omalizumab in asthma: a protein–protein interaction analyses

Abstract Introduction Biomarkers are needed to inform the choice of biologic therapy in patients with asthma given the increasing number of biologics. We aimed to identify proteins associated with response to omalizumab and mepolizumab. Methods Aptamer-based proteomic profiling (SomaScan) was used t...

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Bibliographic Details
Main Authors: Ayobami Akenroye, Tanawin Nopsopon, Laura Cho, Matthew Moll, Scott T. Weiss
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Respiratory Research
Subjects:
Online Access:https://doi.org/10.1186/s12931-023-02620-1