No Functional Role for microRNA-342 in a Mouse Model of Pancreatic Acinar Carcinoma

The intronic microRNA (miR)-342 has been proposed as a potent tumor-suppressor gene. miR-342 is found to be downregulated or epigenetically silenced in multiple different tumor sites, and this loss of expression permits the upregulation of several key oncogenic pathways. In several different cell li...

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Bibliographic Details
Main Authors: James Dooley, Vasiliki Lagou, Emanuela Pasciuto, Michelle A. Linterman, Haydn M. Prosser, Uwe Himmelreich, Adrian Liston
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Oncology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fonc.2017.00101/full