Incorporation of desmocollin‐2 into the plasma membrane requires N‐glycosylation at multiple sites

Desmocollin‐2 (DSC2) is a desmosomal protein of the cadherin family. Desmosomes are multiprotein complexes, which are involved in cell adhesion of cardiomyocytes and of keratinocytes. The molecular structure of the complete extracellular domain (ECD) of DSC2 was recently described, revealing three d...

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Bibliographic Details
Main Authors: Andreas Brodehl, Caroline Stanasiuk, Dario Anselmetti, Jan Gummert, Hendrik Milting
Format: Article
Language:English
Published: Wiley 2019-05-01
Series:FEBS Open Bio
Subjects:
Online Access:https://doi.org/10.1002/2211-5463.12631