In Vitro and In Silico Screening of 2,4,5-Trisubstituted Imidazole Derivatives as Potential Xanthine Oxidase and Acetylcholinesterase Inhibitors, Antioxidant, and Antiproliferative Agents

In Vitro and In Silico Screening of 2,4,5-Trisubstituted Imidazole Derivatives as Potential Xanthine Oxidase and Acetylcholinesterase Inhibitors, Antioxidant, and Antiproliferative Agents

The employment of privileged scaffolds in medicinal chemistry supplies scientists with a solid start in the search for new and improved therapeutic molecules. One of these scaffolds is the imidazole ring, from which several derivatives have shown a wide array of biological activities. A series of 2,...

Full description

Bibliographic Details
Main Authors: Eduardo Noriega-Iribe, Laura Díaz-Rubio, Arturo Estolano-Cobián, Victor Wagner Barajas-Carrillo, José M. Padrón, Ricardo Salazar-Aranda, Raúl Díaz-Molina, Victor García-González, Rocio Alejandra Chávez-Santoscoy, Daniel Chávez, Iván Córdova-Guerrero
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Applied Sciences
Subjects:
imidazole
antiproliferative
antioxidant activities
docking
DPPH
ABTS
Online Access:https://www.mdpi.com/2076-3417/10/8/2889

Internet

https://www.mdpi.com/2076-3417/10/8/2889

Similar Items