Multimodal study of CHI3L1 inhibition and its effect on angiogenesis, migration, immune response and refractive index of cellular structures in glioblastoma

Multimodal study of CHI3L1 inhibition and its effect on angiogenesis, migration, immune response and refractive index of cellular structures in glioblastoma

Glioblastoma is one of the most aggressive tumours with a poor response to treatment and a poor prognosis for patients. One of the proteins expressed in glioblastoma tissue is CHI3L1 (YKL-40), which is upregulated and known for its angiogenesis-supporting and pro-tumour immunomodulatory effects in a...

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Bibliographic Details
Main Authors: Agnieszka Rusak, Igor Buzalewicz, Monika Mrozowska, Benita Wiatrak, Katarzyna Haczkiewicz-Leśniak, Mateusz Olbromski, Alicja Kmiecik, Edward Krzyżak, Aleksandra Pietrowska, Jakub Moskal, Marzenna Podhorska-Okołów, Halina Podbielska, Piotr Dzięgiel
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Biomedicine & Pharmacotherapy
Subjects:
CHI3L1 inhibition
G721-0282
U-87 MG
Glioblastoma
Angiogenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223003086

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http://www.sciencedirect.com/science/article/pii/S0753332223003086

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