Retinoic acid inhibits the angiogenesis of human embryonic stem cell-derived endothelial cells by activating FBP1-mediated gluconeogenesis

Retinoic acid inhibits the angiogenesis of human embryonic stem cell-derived endothelial cells by activating FBP1-mediated gluconeogenesis

Abstract Background Endothelial cells are located in the inner lumen of blood and lymphatic vessels and exhibit the capacity to form new vessel branches from existing vessels through a process called angiogenesis. This process is energy intensive and tightly regulated. Glycolysis is the main energy...

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Main Authors: Zhuangzhuang Yang, Miao Yu, Xuechun Li, Yuanyuan Tu, Chunyan Wang, Wei Lei, Min Song, Yong Wang, Ying Huang, Fengyue Ding, Kaili Hao, Xinglong Han, Xuan Ni, Lina Qu, Zhenya Shen, Shijun Hu
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Stem Cell Research & Therapy
Subjects:
Endothelial cell
Angiogenesis
Retinoic acid
Glycometabolism
Online Access:https://doi.org/10.1186/s13287-022-02908-x

Internet

https://doi.org/10.1186/s13287-022-02908-x

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