Sustained Delivery of the Antiviral Protein Griffithsin and Its Adhesion to a Biological Surface by a Silk Fibroin Scaffold

Sustained Delivery of the Antiviral Protein Griffithsin and Its Adhesion to a Biological Surface by a Silk Fibroin Scaffold

The protein Griffithsin (Grft) is a lectin that tightly binds to high-mannose glycosylation sites on viral surfaces. This property allows Grft to potently inhibit many viruses, including HIV-1. The major route of HIV infection is through sexual activity, so an important tool for reducing the risk of...

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Bibliographic Details
Main Authors: Wenyan Guan, Ning Zhang, Arjan Bains, Airam Martinez, Patricia J. LiWang
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Materials
Subjects:
silk fibroin
HIV prevention
Griffithsin
drug delivery
adhesion
Online Access:https://www.mdpi.com/1996-1944/16/16/5547

Internet

https://www.mdpi.com/1996-1944/16/16/5547

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