mTOR Inhibitors Induce Erythropoietin Resistance in Renal Transplant Recipients

mTOR Inhibitors Induce Erythropoietin Resistance in Renal Transplant Recipients

AimTo elucidate the role of mTOR inhibitors on iron, hepcidin and erythropoietin-mediated regulation of hemopoiesis in stable renal transplant recipients (RTR).BackgroundImpaired hemopoiesis is common following renal transplantation managed using mTOR inhibitors. The mechanisms responsible are uncer...

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Bibliographic Details
Main Authors: Reece Jefferies, Harish Puttagunta, Anoushka Krishnan, Ashley Irish, Ramyasuda Swaminathan, John K. Olynyk
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Medicine
Subjects:
renal transplant
mTOR inhibitor
anemia
iron deficiency
hepcidin
erythropoietin
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.722058/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2022.722058/full

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