Oleic acid released by sensory neurons inhibits TRPV1-mediated thermal hypersensitivity via GPR40

Oleic acid released by sensory neurons inhibits TRPV1-mediated thermal hypersensitivity via GPR40

Summary: Noxious stimuli activate nociceptive sensory neurons, causing action potential firing and the release of diverse signaling molecules. Several peptides have already been identified to be released by sensory neurons and shown to modulate inflammatory responses and inflammatory pain. However,...

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Bibliographic Details
Main Authors: Maksim Sendetski, Saskia Wedel, Kenta Furutani, Lisa Hahnefeld, Carlo Angioni, Jan Heering, Béla Zimmer, Sandra Pierre, Alexandra-Maria Banica, Klaus Scholich, Sorin Tunaru, Gerd Geisslinger, Ru-Rong Ji, Marco Sisignano
Format: Article
Language:English
Published: Elsevier 2024-08-01
Series:iScience
Subjects:
Biological sciences
Neuroscience
Molecular neuroscience
Sensory neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224017772

Internet

http://www.sciencedirect.com/science/article/pii/S2589004224017772

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