Human Mitoribosome Biogenesis and Its Emerging Links to Disease

Human Mitoribosome Biogenesis and Its Emerging Links to Disease

Mammalian mitochondrial ribosomes (mitoribosomes) synthesize a small subset of proteins, which are essential components of the oxidative phosphorylation machinery. Therefore, their function is of fundamental importance to cellular metabolism. The assembly of mitoribosomes is a complex process that p...

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Bibliographic Details
Main Authors: Maria Isabel G. Lopez Sanchez, Annika Krüger, Dmitrii I. Shiriaev, Yong Liu, Joanna Rorbach
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
mitochondria
mitoribosome
assembly factors
rRNA
mitochondrial disease
Online Access:https://www.mdpi.com/1422-0067/22/8/3827

Internet

https://www.mdpi.com/1422-0067/22/8/3827

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