Ginsenosides, potential TMPRSS2 inhibitors, a trade-off between the therapeutic combination for anti-PD-1 immunotherapy and the treatment of COVID-19 infection of LUAD patients

Ginsenosides, potential TMPRSS2 inhibitors, a trade-off between the therapeutic combination for anti-PD-1 immunotherapy and the treatment of COVID-19 infection of LUAD patients

Background: Acting as a viral entry for coronavirus to invade human cells, TMPRSS2 has become a target for the prevention and treatment of COVID-19 infection. Before this, TMPRSS2 has presented biological functions in cancer, but the roles remain controversial and the mechanism remains unelucidated....

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Bibliographic Details
Main Authors: Mei Meng, Rui Gao, Zixue Liu, Fengxiang Liu, Shiyu Du, Yizhi Song, Jian He
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Pharmacology
Subjects:
TMPRSS2
LUAD
biomarker
tumor-infiltrating lymphocytes
prognosis
ginsenosides
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1085509/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1085509/full

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