Coexistence of blaNDM-1 and blaIMP-4 in One Novel Hybrid Plasmid Confers Transferable Carbapenem Resistance in an ST20-K28 Klebsiella pneumoniae

Coexistence of blaNDM-1 and blaIMP-4 in One Novel Hybrid Plasmid Confers Transferable Carbapenem Resistance in an ST20-K28 Klebsiella pneumoniae

ObjectivesWe identified a novel hybrid plasmid simultaneously carrying blaNDM-1 and blaIMP-4 in an ST20-K28 carbapenem-resistant Klebsiella pneumoniae (CRKP) strain AZS099 and reported its detailed genetic and phenotypic characterization.MethodsAntimicrobial susceptibility was characterized using br...

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Bibliographic Details
Main Authors: Xinmiao Jia, Peiyao Jia, Ying Zhu, Wei Yu, Xue Li, Jingyuan Xi, Xiaoyu Liu, Kang Liao, Yingchun Xu, Bin Cheng, Qiwen Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Microbiology
Subjects:
carbapenemase
NDM
IMP
Klebsiella pneumoniae
plasmid
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.891807/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.891807/full

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